Table 5.
Association of haplotypes with CML risk and IM response
|
c.1236
C>T |
c.3435
C>T |
Total freq. |
Control
Freq. |
Case freq. |
p
value |
OR* (95%CI) | CCyR freq. | Non-CCyR freq. | Total freq. |
p
value |
OR* (95%CI) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| T | T | 0.4428 | 0.4691 | 0.4691 | Ref. | 1 | 0.5002 | 0.3441 | 0.4144 | - | 1 |
| C | C | 0.3746 | 0.3791 | 0.3791 | 0.66 | 0.89 (0.54-1.48) | 0.3184 | 0.4089 | 0.3684 | 0.07 | 2.11 (0.94-4.72) |
| T | C | 0.1001 | 0.0859 | 0.0859 | 0.86 | 1.08 (0.47-2.49) | 0.0907 | 0.1374 | 0.1162 | 0.2 | 2.36 (0.63-8.81) |
| C | T | 0.0825 | 0.0659 | 0.0659 | 0.58 | 1.29 (0.53-3.15) | 0.0907 | 0.1096 | 0.1009 | 0.41 | 1.72 (0.48-6.24) |
freq, frequency; Ref: reference; *logistic regression model adjusted for sex, age, and smoking status