Table 1.

Animal characteristics, blood analyses, and IOD

Parameter (unit)	NC (n = 8)	HFD (n = 8)	HFD+EA (n = 8)
Body weight (g)
0 weeks 2 weeks 4 weeks 6 weeks 8 weeks	293.88 ± 32.91 303.75 ± 49.70 310.00 ± 47.23 312.50 ± 43.87 305.88 ± 62.72	356.50 ± 65.96 363.25 ± 76.26 386.43 ± 89.68 392.59 ± 57.31 401.63 ± 91.81	352.62 ± 65.40 332.75 ± 67.28 326.62 ± 53.59 307.12 ± 42.11# 294.13 ± 53.78#
Food intake (g)
0 weeks 2 weeks 4 weeks 6 weeks 8 weeks	25.77 ± 4.87 25.97 ± 4.25 26.85 ± 2.77 25.41 ± 4.83 21.81 ± 3.64	19.46 ± 4.47** 22.27 ± 5.50 22.80 ± 4.44* 20.61 ± 3.50* 18.00 ± 2.07*	16.51 ± 2.25** 24.67 ± 2.68 20.92 ± 3.10** 19.62 ± 2.56** 18.21 ± 3.78*
Water intake (mL)
0 weeks 2 weeks 4 weeks 6 weeks 8 weeks	35.62 ± 8.24 41.62 ± 8.03 55.25 ± 8.73 29.50 ± 5.50 30.87 ± 5.76	40.75 ± 9.64 47.62 ± 8.51 66.37 ± 7.78** 36.12 ± 8.37 37.87 ± 5.66*	32.62 ± 9.30 36.12 ± 6.46## 37.62 ± 9.15## 26.75 ± 6.04# 25.12 ± 7.71##
FBG (mmol/L)
0 weeks 2 weeks 4 weeks 6 weeks 8 weeks	3.40 ± 0.95 3.17 ± 0.55 3.86 ± 0.39 3.78 ± 0.38 3.41 ± 0.27	4.57 ± 0.92** 4.71 ± 0.43** 4.73 ± 0.59** 4.01 ± 0.30 3.71 ± 0.48	4.65 ± 0.66** 3.50 ± 0.69## 4.07 ± 0.55# 3.91 ± 0.30 3.60 ± 0.52
PPG (mmol/L)
0 weeks 2 weeks 4 weeks 6 weeks 8 weeks	5.32 ± 0.66 4.48 ± 0.57 4.56 ± 0.47 4.78 ± 0.53 5.38 ± 0.43	6.31 ± 0.78** 5.22 ± 0.61* 5.27 ± 0.49* 5.47 ± 0.73* 5.64 ± 0.56	6.12 ± 0.59* 4.56 ± 0.59# 4.47 ± 0.66# 4.48 ± 0.79# 5.24 ± 0.55
IOD of GLUT4	0.352 ± 0.018	0.297 ± 0.011*	0.338 ± 0.015 #

Data are expressed as the mean ± SD. Differences between means were determined using ANOVA followed by LSD multiple comparison test. *P < 0.05 vs. NC; **P < 0.01 vs. NC; # P < 0.05 vs. HFD; ## P < 0.01 vs. HFD. IOD: integrated optical density.