Fig 7. V1V2 responses were associated with V1V2-specific ADCP responses in RV144 vaccinees.
Canonical sPLS model highlighted Ab binding features which covaried with the Fc effector functions for vaccine (A) and placebo (B) recipients. Colors show the direction of the associations: positive (dark purple) and inverse (dark cyan). (C) Correlation network highlighting the vaccine RF-selected predictive features that correlated with Fc effector functions. (D) Scatter plots showing significant Spearman correlations between V1V2-specific ADCP and binding responses in vaccine recipients.