Fig 6. Relative usage of TMPRSS2 and Cathepsin B/L pathways during SARS-CoV and SARS-CoV-2 entry.

The fraction of infection events unaffected either by TMPRSS2 or Cathepsin B/L inhibitors in excess were used to estimate the relative entry pathway usage in different cells lines. Data and sources are in S2 Table. The analysis follows the formalism outlined in the Methods.