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. Author manuscript; available in PMC: 2021 Jun 22.
Published in final edited form as: Phys Med Biol. 2020 Jun 22;65(12):125017. doi: 10.1088/1361-6560/ab9705

Figure 4.

Figure 4.

Effects of pFUS pretreatment on NP penetration. (A) A representative tumor section indicating the three ROIs employed for quantifying the NP (200 nm) distributions (bar = 2 mm). (B) Comparison of relative NP distributions in the three ROIs for control and pFUS treated tumors (n = 7). An 18.1% decrease in NP delivery was found in the outermost region (ROI 3) in the pFUS treated tumors, compared to the control tumors. Conversely, in the innermost region (ROI 1), a 57% increase was found in the pFUS treated tumors compared to controls.