Table 1. Comparison of M2 muscarinic G protein–coupled receptor diffusion (Dlat) in mouse primary cardiomyocytes, mouse heart muscle slices (at 23°C and 37°C), zebrafish heart slices, and neuronal structures identified within the mouse heart slices.
Mouse cultured cardiomyocytes (23°C) | Mouse tissue slice (23°C) | Mouse tissue slice (37°C) | Mouse neuritis (23°C) | Zebrafish tissue slice (23°C) | |
---|---|---|---|---|---|
Dlat ± SD (µm2 ⋅ s−1) | 0.16 ± 0.04 | 0.62 ± 0.11 | 1.3 ± 0.2 | 0.4a | 0.7 ± 0.06 |
Trajectories (n) | 3,812 | 3,260 | 6,741 | 1,882 | 2,208 |
Cells (n) | 8 | 17 | 11 | N/A | 11 |
N/A, not available
The Dlat value stated here assumes free 2-D motion, whereby the gradient of the MSD-versus-dT plot is equal to 4Dlat. Please see Discussion section for further explanation.