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. 2020 Dec 16;153(1):e202012657. doi: 10.1085/jgp.202012657

Table 1. Comparison of M2 muscarinic G protein–coupled receptor diffusion (Dlat) in mouse primary cardiomyocytes, mouse heart muscle slices (at 23°C and 37°C), zebrafish heart slices, and neuronal structures identified within the mouse heart slices.

Mouse cultured cardiomyocytes (23°C) Mouse tissue slice (23°C) Mouse tissue slice (37°C) Mouse neuritis (23°C) Zebrafish tissue slice (23°C)
Dlat ± SD (µm2 ⋅ s−1) 0.16 ± 0.04 0.62 ± 0.11 1.3 ± 0.2 0.4a 0.7 ± 0.06
Trajectories (n) 3,812 3,260 6,741 1,882 2,208
Cells (n) 8 17 11 N/A 11

N/A, not available

a

The Dlat value stated here assumes free 2-D motion, whereby the gradient of the MSD-versus-dT plot is equal to 4Dlat. Please see Discussion section for further explanation.