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. 2020 Dec 16;218(3):e20200547. doi: 10.1084/jem.20200547

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© 2020 Lu et al.

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Figure S2. — Bcl6^f/fFoxp3-Cre animals have reduced HA-specific GC B cells and antibody response compared with Foxp3-Cre littermate controls. (A) Analysis of the GC B cell responses in Foxp3-Cre and Bcl6^f/f Foxp3-Cre mice at day 38 following influenza virus infection. Left: Representative plots of the HA⁺ GC B cell responses in Foxp3-Cre and Bcl6^f/f Foxp3-Cre mice at day 38 p.i. Right: Frequency and number of cells as indicated by the gates shown on the left. (B) ELISA analysis of serum influenza-specific antibody titers in Bcl6^f/f Foxp3-Cre and littermate wild-type Foxp3-Cre mice at day 38 p.i. Statistical analyses were performed using the unpaired two-tailed Student’s t test (*, P < 0.05; **, P < 0.01). Data are pooled from two independent experiments with four to six mice per group. AUC, area under the curve.