TABLE 1.

Enzyme assay showing effect of ETVTP on HIV RT

HIV RT	dNTP	kpol	Kd,dNTP	kpol/Kd,dNTP
		s−1	μM	μM−1s−1
WT	dGTP	18.3 ± 1.30	1.76 ± 0.51	10.4 ± 3.11
	ETVTP	0.107 ± 0.007	2.23 ± 0.67	0.048 ± 0.015
	CBVTP	2.26 ± 0.24	27.8 ± 7.68	0.081 ± 0.024
M184V	dGTP	34.4 ± 3.36	5.93 ± 2.04	5.8 ± 2.1
	ETVTP	0.019 ± 0.002	27.8 ± 6.12	0.0007 ± 0.0002
	CBVTP	0.887 ± 0.078	14.1 ± 3.9	0.063 ± 0.018

Assay details are as described in (Refs. 14 and 19).