Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 18;11:6411. doi: 10.1038/s41467-020-20092-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a Expression profiles of cell marker genes that are specific to or enriched in the tegument clusters. Genes validated by ISH are marked in red. b annexin B2+ cells have taken up the fluorescent dextran. Yellow arrowheads indicate double-positive cells. Single confocal sections are shown. c Double FISH of Tegument 1 markers annexin B2 (Smp_077720) and Smp_022450. The majority of the cells show co-localisation (white signal). Left: MIP; right: zoomed in confocal sections. vs: ventral sucker; gc: germinal cell cluster. d Double FISH of Tegument 1 markers Smp_022450 and meg3 (Smp_138070). The majority of the cells show co-localisation (white signal). e Double FISH of Tegument 1 marker (Smp_022450) with ccdc74 (Smp_030010), MIP. The majority of cells show co-localisation (white signal), while a subset of cells in the neck region of the worm show single positive cells for Tegument 2 markers. f, g Double FISH of Tegument 2 marker mboat (Smp_169040) and f Tegument 1 marker annexin B2 (Smp_077720) and g oesophageal gland marker meg4 (Smp_307220), single confocal sections. Green arrowhead: mboat+ cells; white arrowhead: double-positive cells. h Schematic that summarises the tegument cell populations in 2-day old schistosomula. Marker genes identified in the current study are indicated in red. All previously reported genes are shown in black. The numbers of ISH experiments performed for each gene are listed in ‘Methods’ and Supplementary Data 7.