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. 2020 Dec 18;10:22286. doi: 10.1038/s41598-020-79002-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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HIV specific T lymphocyte response. The ELISpot assay, that quantifies interferon-γ secretion against different peptide pools covering p17, p24, sp1, sp2, gag, pol, nef and env sequences, was used. Samples were taken before the intensification with maraviroc during the initial study (grey bars) and when antiretroviral treatment was resumed after the ATI during the amended study (black bars). Data are are shown as the number of cells secreting interferon-γ against the indicated peptide per 10⁶ peripheral blood mononuclear cells (PBMCs). The dotted grey line indicates the threshold for positivity (50 SFC per million PBMCs). SFC, spot forming cells.