Figure 1.

Summary of IOP changes in vehicle and dexamethasone (DEX)-treated mice

(A) Change in IOP after 4 weeks of vehicle (red, n = 9) or DEX (blue, n = 17) delivery via a micro-osmotic pump. Dashed arrows represent the differences between population average at baseline and after treatment, while solid arrows represent the average change in IOP per mouse after treatment. (B) Cello plots show the IOP increase (mmHg) following treatment with either cyclodextrin vehicle (red) or DEX (blue) for 4 weeks. The white line represents the geometric mean, the dark red/blue bands indicate the 95% CI, and the light red/blue regions are the distributions of the data. Each data point represents the IOP increase (mmHg) for each individual animal. p values are represented by asterisks.