Fig. 5.

Evaluation of antiadhesion efficacy at days 7 and 14 after surgery in a rat sidewall defect–cecum abrasion adhesion model. (A) Postoperative adhesions were observed in the untreated control and Interceed film groups while no adhesion was observed in rats treated with PCBAA on days 7 and 14 after the surgery. (B and C) Distribution of adhesion scores (B) and weight loss (C) in the untreated, film, and PCBAA groups on days 7 and 14 after the surgery. The results are presented as mean ± SD (n = 6). **P < 0.01; NS, not significant. (D) Representative histology images (H&E and Masson trichrome staining) of tissues from different groups on days 7 and 14 after surgery, respectively. AW: abdominal wall; CE: cecal mucosa; Me: mesothelial layer; SK: skeletal muscle of AW. The deposited collagen in the adhesion site was stained in blue while muscle showed red in Masson trichrome staining. (Scale bar, 400 μm.)