Fig. 6.

Establishment of a rat repeated-injury model to evaluate the antiadhesion efficacy of PCBAA and commercial Interceed film. (A) Schematic of the experimental schedule. (B) Procedures to establish the rat repeated-injury model and apply antiadhesion materials onto the reinjured sites. Abdominal wall defect–cecum abrasion model was established in SD rats at the first surgery (day −7). The established adhesion was lysed at the second surgery and the repeated injury was performed by reabrading the detached abdominal wall and cecum (day 0). Then, PCBAA and Interceed film were applied on the reinjured abdominal wall and cecum.