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. 2020 Nov 1;23(12):101750. doi: 10.1016/j.isci.2020.101750

Scheme 1.

Scheme 1

Schematic Representation of Polydopamine Polymerization Mechanism

(A) PDA artificial receptors can be catalyzed using G-quadruplex DNAzyme and specific characteristics of TME. (B) PDA can only deposit on the cancerous cell membrane and act as artificial receptors to deliver protein drugs and amino-containing small drugs to them.