Figure 9.

Brain histopathology; Group 4: group of rats experimentally inducted and treated by reference drug: cerebral cortex (A), subiculum in hippocampus (B), fascia dentata and hilus in hippocampus (C), striatum (D) and cerebellum (E). (H&E staining, x10, scale bar = 50μm). Cerebral cortex and Subiculum in hippocampus showed no histopathological alteration. Most neurons of the Fascia dentata and hilus in hippocampus showed nuclear pyknosis and degeneration (indicated by white arrows). The striatum showed multiple focal eosinophilic large plagues formation with loss of the neurons was noticed. The cerebellum recorded no histopathological alteration.