Fig. 2.

Box plot representing minimum, first quartile, median, third quartile, and maximum relative change (%) in (A) microvessel density (MVD) and density of proliferating vessels following vanucizumab treatment (day 29 vs. baseline) in tumor and skin-wound-healing biopsies, and (B) density of angiopoietin-2-positive (Ang2+) vessels following vanucizumab treatment (day 29 vs. baseline) in tumor biopsies (due to the small sample size, assessment was not possible in skin biopsy samples). Extreme values are located outside the limits of the box.