Additional Table 1.

Non-neuronal expression of the machinery required for dopamine synthesis, storage, uptake and metabolism

Cell type	Synthesis	Storage	Uptake	Metabolism
Microglia	Mastroeni et al., 2009; Morales et al., 2017	n/a	Mastroeni et al., 2009	Redell et al., 2007; Meiser et al., 2013
Astrocytes	Asanuma and Miyazaki, 2016; Morales et al., 2017	Petrelli et al., 2018; Matt and Gaskill, 2019	Morales et al., 2017; Matt and Gaskill, 2019	Bisaglia et al., 2013; Schain et al., 2017; Winner et al., 2017; Petrelli et al., 2018
Monocyte	Gaskill et al., 2012; Mackie et a., 2018; Gopinath et al., 2020	Gaskill et al., 2012; Gopinath et al., 2020	Gaskill et al., 2012; Mackie et a., 2018; Gopinath et al., 2020	n/a
Macrophages	(Gaskill et al., 2012)	Gaskill et al., 2012	Gaskill et al., 2012; Mackie, et al., 2018	n/a
T-lymphocytes	Musso et al., 1996; Cosentino, et al., 2006; Wang et al., 2016	Cosentino, et al., 2006; Amenta et al., 2001	Amenta et al., 2001	Balsa et al., 1989
B-lymphocytes	Talhada et al., 2018	Pacheco et al., 2014	n/a	Balsa et al., 1989
Dendritic cells	Nakano et al., 2009; Prado et al., 2012; Pacheco et al., 2014	Nakano et al., 2009; Prado et al., 2012	Prado et al., 2012	Prado et al., 2012
Neutrophils	Cosentino et al., 1999	Cosentino et al., 1999	Cosentino et al., 1999	Bidart et al., 1983
Eosinophils	n/a	n/a	n/a	Bidart et al., 1983
Mast cells	Ronneberg et al., 2012	Anlauf et al., 2006	n/a	n/a

(COMT and/or MAO) of dopamine. Several non-neuronal cell types are able to produce, transport and metabolise dopamine in a manner independent of dopamine neurotransmission. COMT: Catechol-O-methyltransferase; DAT: DA transporter; MAO: monoamine oxidase; TH: tyrosine hydroxylase; VMAT2: vesicular monoamine transporter 2.