TABLE 2.
Plasma parameters
| Parameter | b Control range | All patients | BW‐stable | Cachexia | P value |
|---|---|---|---|---|---|
| n = 52 | n = 35 | n = 17 | |||
| a BNP (pg/mL) | 10–80 | 1606 ± 1278 | 1411 ± 1272 | 2007 ± 1229 | * 0.010 |
| Creatinine (μmol/L) | 64–104 | 109 ± 42 | 106 ± 31 | 114 ± 60 | 0.596 |
| Total protein (g/L) | 64–79 | 62 ± 6 | 63 ± 7 | 61 ± 4 | 0.798 |
| C reactive protein (g/L) | < 5 | 9 ± 12 | 8 ± 9 | 11 ± 17 | 0.525 |
| Haemoglobin (g/L) | 135–175 | 126 ± 15 | 127 ± 15 | 124 ± 13 | 0.437 |
| Total cholesterol (mmol/L) | 2.9–5.1 | 3.7 ± 1.1 | 3.7 ± 1.1 | 3.8 ± 1.1 | 0.782 |
| Triglycerides (mmol/L) | 0.5–1.7 | 1.3 ± 0.7 | 1.3 ± 0.8 | 1.2 ± 0.5 | 0.415 |
| TSH (mUI/L) | 0.4–4.9 | 3.9 ± 3.4 | 3.8 ± 3.8 | 4.2 ± 2.5 | 0.803 |
| fT3 (pmol/L) | 2.9–4.9 | 3.4 ± 0.8 | 3.4 ± 0.8 | 3.3 ± 0.9 | 0.655 |
| fT4 (pmol/L) | 9–19 | 14 ± 4 | 14 ± 3 | 16 ± 5 | 0.223 |
| Cortizol (nmol/L) | 166–507 | 436 ± 241 | 451 ± 265 | 407 ± 187 | 0.493 |
| Fasting plasma glucose (mmol/L) | 3.6–5.6 | 5.8 ± 1.2 | 6 ± 1.3 | 5.4 ± 1.1 | 0.112 |
| Fasting plasma insulin (μIU/mL) | 4.1 ± 3.8 | 4.2 ± 4.1 | 3.9 ± 3.1 | 0.846 | |
| HOMA‐IR | 1.0 ± 1.0 | 1.1 ± 1.1 | 0.9 ± 0.7 | 0.492 | |
| Haemoglobin A1C (mmol/mol) | 20–42 | 49 ± 10 | 50 ± 12 | 44 ± 6 | 0.017 |
| Bilirubin (μmol/L) | 3–20 | 21 ± 11 | 21 ± 12 | 23 ± 11 | 0.584 |
| Sodium (mmol/L) | 137–144 | 135 ± 4 | 136 ± 4 | 134 ± 5 | 0.321 |
| Potassium (mmol/L) | 3.5–5.1 | 4.1 ± 0.6 | 4.1 ± 0.7 | 4.2 ± 0.4 | 0.219 |
Data are shown for all the patients, or two subgroups of the patients split based on BW trajectories during the previous 6 months (BW‐stable vs. Cachexia). Data are means ± SD. Bold, statistical significant difference.
a
Median (Q1–Q3) for BNP: all patients, 1283 (599–2413); BW‐stable, 707 (445–1815); Cachexia 1650 (902–2506).
b
Control (normal) range at the IKEM Central Laboratory; data are for both genders, only the BNP data are for man at 55–65 years of age, for women of this age: 10–155 pg BNP/ml plasma. HOMA, homeostasis model assessment;
*
For log‐transformed data.