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. 2020 Sep 28;11(6):1830–1849. doi: 10.1002/jcsm.12612

Table 2.

Additional parameters obtained by echocardiography

Sham PAB AOB Sham PAB AOB
7 weeks 7 weeks 7 weeks 22–26 weeks 22 weeks 26 weeks
(n = 14) (n = 14) (n = 14) (n = 20) (n = 10) (n = 10)
LVEDD (mm) 6.44 ± 0.06 6.73 ± 0.04 6.47 ± 0.05 6.62 ± 0.09 5.79 ± 0.12 * 8.73 ± 0.08 * , §§
RVEDD (mm) 2.51 ± 0.15 2.22 ± 0.21 2.10 ± 0.09 2.43 ± 0.18 5.85 ± 0.23 ** 2.81 ± 0.14 §§
LVPWT (mm) 1.35 ± 0.11 1.27 ± 0.04 1.72 ± 0.08 * , § 1.42 ± 0.16 1.45 ± 0.12 2.01 ± 0.13 * , §
IVSD (mm) 0.95 ± 0.03 1.02 ± 0.04 1.13 ± 0.02 * 0.98 ± 0.02 1.25 ± 0.09 * , 1.64 ± 0.04 ** , §
RVWTD (mm) 0.30 ± 0.02 0.42 ± 0.05 * 0.33 ± 0.04 0.33 ± 0.04 0.52 ± 0.06 ** , 0.35 ± 0.03 §§
LV SV (μL) 143.4 ± 9.9 145.1 ± 6.3 181.7 ± 15.2 * , § 151.2 ± 8.5 148.6 ± 8.2 121.7 ± 12.1 * , , §
LV CO (mL/min) 46.7 ± 1.2 46.2 ± 1.9 58.6 ± 2.5 * , § 47.4 ± 0.9 47.8 ± 3.3 33.9 ± 1.2 ** , †† , §

AOB, ascending aortic banding; PAB, pulmonary artery banding.

Echocardiographic evaluation of LVEDD (left ventricular end‐diastolic diameter), RVEDD (right ventricular end‐diastolic diameter), LVPWT (left ventricular posterior wall thickness in diastole), IVSD (interventricular septum in diastole), RVWTD (right ventricular wall thickness in diastole), LV SV (stroke volume = left ventricular end‐diastolic − left ventricular end‐systolic volume), and LV CO (cardiac output = stroke volume × heart rate).

*

P < 0.05.

**

P < 0.01 vs. respective age‐matched sham.

P < 0.05.

††

P < 0.01 vs. respective 7 week animals.

§

P < 0.05.

§§

P < 0.01 vs. respective age‐matched PAB animals.