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. 2021 Jan;27(1):80–98. doi: 10.1261/rna.074724.120

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© 2021 Duan et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 2. — The performance of the representative models on the transcripts assembled from the simulated data. Based on the golden-standard sequence sets (golden_human and golden_mouse), simulated Illumina-sequencing data sets were generated by Polyester with five sequencing depths: 30× (which means that, on average, 30 reads were simulated from each transcript), 100×, 300×, 600×, and 1200×. (A) The relationship between assembled transcripts and its templates. The CRE transcript shares an identical intron chain with its template; the CRC transcript is covered by its template; and the CRJ transcript shares at least one splicing site with its template. (B) Box plots for the MCC of all testing models on the simulated data of different sequencing depths. (C) Performance of representative models on human CRC transcripts. (D) Performance of representative models on human CRJ transcripts.