Table 1.
Clinical data | Patient 1 | Patient 2 | Patient 3 |
---|---|---|---|
Age (years) | 10 | 16 | 7 |
Sex (F/M) | F | F | M |
Weight (kg) | 20,5 | 68 | 26 |
SCD Genotype | SS | SS | SC |
Baseline Hemoglobin (g/dL) | 7,5 | 9 | 9 |
Baseline HBF (%) | 26,3 | 7,6 | 0 |
Hydroxyurea (years of use) | 7 | 10 | – |
Supplemental O2 requirement | Yes | Yes | Yes |
Fever before admission | No | No | No |
Fever during hospital stay | Yes | Yes | Yes |
Blood transfusion during hospital stay | Yes | Yes | Yes |
Hospitalization days | 8 | 19 | 24 |
Antibiotics | Ceftriaxone and clarithromycin | Ceftriaxone, clarithromycin and piperacillin/tazobactam | Ceftriaxone, azithromycin and vancomycin |