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. 2020 Dec 16;8:e10494. doi: 10.7717/peerj.10494

Table 3. P values for ΔCt comparisons between groups with different clinicopathological characteristics, after normalization to miR-222-3p.

Clinicopathological characteristics miR-145-5p miR-16-5p miR-191-5p miR-21-5p miR-210-3p miR-29c-3p
BC patients group
ER- vs ER+ 0.630 0.714 0.862 0.269 0.832 0.428
PR- vs PR+ 0.287 0.627 0.553 0.339 0.577 0.122
HER2- vs HER2+ 0.043 0.559 0.006 0.379 0.191 0.771
N0 vs N1-3 0.086 0.441 0.190 0.246 0.810 0.360
Ki-67 <20% vs ≥20% 0.096 0.134 0.089 0.003 0.708 0.405
Tumor grade: G2 vs G3 0.033 0.066 0.644 0.297 0.007 0.676
Age: <50 vs. ≥50 0.257 0.987 0.906 0.371 0.191 0.749
Menarche age: ≤14 vs >14 0.009 0.743 0.166 0.022 0.802 0.862
Menopausal status: pre- vs post 0.096 0.908 0.517 0.249 0.118 0.881
Age of first birth: ≤22 vs >22 0.063 0.683 0.345 0.873 0.102 0.276
Number of children: ≤2 vs >2 0.987 0.347 0.139 0.107 0.521 0.099
Unsuccessful pregnancies: 0 vs >0 0.316 0.061 0.713 0.163 0.300 0.099
Family history of cancer: no vs yes 0.576 0.499 0.550 0.143 0.286 0.143
Alcohol consumption: no vs yes 0.093 0.378 0.233 0.745 0.379 0.565
Control group
Age: <50 vs. ≥50 0.501 0.986 0.102 0.842 0.137 0.008
Menarche age: ≤14 vs >14 0.402 0.118 0.087 0.581 0.276 0.402
Menopausal status: pre- vs post- 0.240 0.186 0.872 0.553 0.815 0.114
Age of first birth: ≤22 vs >22 0.486 0.929 0.166 0.442 0.401 0.901
Number of children: ≤2 vs >2 0.478 0.316 0.392 0.011 0.235 0.730
Unsuccessful pregnancies: 0 vs >0 0.696 0.272 0.886 0.067 0.127 0.726
Family history of cancer: no vs yes 0.796 0.438 0.029 0.592 0.179 0.564
Alcohol consumption: no vs yes 0.352 0.215 0.780 0.682 0.352 0.249

Note.

p values <0.05 are in bold.