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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Invest Dermatol. 2020 May 15;140(12):2505–2514. doi: 10.1016/j.jid.2020.04.015

Figure 4. Loss of TSG-6 in skin upregulates the expression of the pro-inflammatory cytokine TNFα.

Figure 4.

(a), Western analysis of unwounded skin (upper panel) and of 7-day healing wounds (lower panel), show higher TNFα protein expression in TSG-6 null mice as compared to WT mice. (b), Quantification of multiple Western blot experiments reveals significantly higher expression of TNFα in TSG-6 null skin, both before wounding and in the first 7 days after wounding; mean ± SEM; significance levels are indicated by P-values above the bars (Mann-Whitney Rank Sum test after Shapiro-Wilk tests for normality).