Table 2.
Correlation Between miR-487b Expression Levels and Clinical Features
| miR-487b Expression | ||||
|---|---|---|---|---|
| Parameters | Cases No. (n = 87) | Low (n = 41) | High (n = 46) | P Value |
| Gender | ||||
| Male | 61 | 29 | 32 | .906 |
| Female | 26 | 12 | 14 | |
| Age, y | ||||
| <60 | 29 | 11 | 18 | .224 |
| ≥60 | 58 | 30 | 28 | |
| Tumor size, cm | ||||
| <5 | 56 | 29 | 27 | .242 |
| ≥5 | 31 | 12 | 19 | |
| AFP, ng/mL | ||||
| <20 | 12 | 6 | 6 | .830 |
| ≥20 | 75 | 35 | 40 | |
| Liver cirrhosis | ||||
| Present | 46 | 18 | 28 | .114 |
| Absent | 41 | 23 | 18 | |
| ALT | ||||
| Normal | 13 | 9 | 4 | .083 |
| Elevated level | 74 | 32 | 42 | |
| AST | ||||
| Normal | 11 | 8 | 3 | .069 |
| Elevated level | 76 | 33 | 43 | |
| Differentiation | ||||
| Poor | 40 | 22 | 18 | .175 |
| Well + moderate | 47 | 19 | 28 | |
| BCLC stage | ||||
| A | 52 | 31 | 21 | .004 |
| B | 35 | 10 | 25 | |
| TNM stage | ||||
| I & II | 50 | 30 | 20 | .005 |
| III | 37 | 11 | 26 | |
Abbreviations: AFP, alpha-fetoprotein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BCLC, Barcelona Clinic Liver Cancer; TNM, Tumor Node Metastasis.