Table 1.
Demographic and clinical characteristics of 23 patients with COVID-19.
| Variable | Total (N = 23) | VTE (n = 19) | Non-VTE (n = 4) | P value |
|---|---|---|---|---|
| Male, n (%) | 14 (60.1) | 12 (63.2) | 2 (50.0) | 1.000 |
| Age (years) | 42.7 ± 12.0 | 43.2 ± 12.1 | 40.8 ± 13.5 | 0.725 |
| BMI | 23.6 ± 2.8 | 23.3 ± 2.4 | 25.1 ± 4.4 | 0.260 |
| Onset of symptoms | ||||
| Fever, n (%) | 15 (65.2) | 12 (63.2) | 3 (75.0) | 1.000 |
| Cough, n (%) | 12 (52.2) | 10 (52.6) | 2 (50.0) | 1.000 |
| Sputum, n(%) | 3 (13.0) | 3 (15.8) | 0 (0.0) | 1.000 |
| Fatigue, n (%) | 6 (26.1) | 5 (26.3) | 1 (25.0) | 1.000 |
| Dyspnea, n (%) | 1 (4.3) | 0 (0.0) | 1 (25.0) | 0.174 |
| Diarrhea, n (%) | 5 (21.7) | 4 (21.1) | 1 (25.0) | 1.000 |
| Sore throat, n (%) | 4 (17.4) | 3 (15.8) | 1 (25.0) | 1.000 |
| Anosmia, n(%) | 4 (17.4) | 3 (15.8) | 1 (25.0) | 1.000 |
| Vital signs | ||||
| Temperature (℃) | 37.7 ± 0.7 | 37.7 ± 0.8 | 37.8 ± 0.8 | 0.798 |
| Respiratory rate (breaths per min) | 19.4 ± 1.0 | 19.4 ± 1.0 | 19.0 ± 1.2 | 0.466 |
| Heart rate (beats per min) | 86.4 ± 10.6 | 84.8 ± 9.6 | 93.8 ± 13.4 | 0.128 |
| SBP (mmHg) | 125.7 ± 16.7 | 125.3 ± 17.0 | 127.5 ± 17.5 | 0.826 |
| DBP (mmHg) | 80.3 ± 10.8 | 79.7 ± 10.9 | 83.3 ± 11.2 | 0.560 |
| Padua prediction score | 1 (1, 4) | 1 (1, 4) | 1 | 0.794 |
| Hematological and infection-related indices | ||||
| White blood cells (×109/L) | 6.7 ± 1.7 | 7.1 ± 1.6 | 5.1 ± 1.3 | 0.042 |
| Lymphocytes (×109/L) | 2.3 ± 0.7 | 2.4 ± 0.7 | 1.8 ± 0.4 | 0.115 |
| Neutrophil (×109/L) | 4.1 ± 1.5 | 4.4 ± 1.4 | 2.8 ± 1.1 | 0.056 |
| Neutrophils/lymphocytes | 2.5 ± 1.1 | 2.5 ± 1.1 | 2.1 | 0.458 |
| Platelets (×109/L) | 187.3 ± 61.8 | 182.2 ± 61.0 | 211.4 ± 68.9 | 0.404 |
| Hemoglobin (g/L) | 134.8 ± 20.0 | 136.6 ± 18.2 | 126.5 ± 29.1 | 0.374 |
| Coagulation function index | ||||
| D-dimer (μg/mL) | 3.3 ± 13.2 | 0.5 ± 0.5 | 0.4 ± 0.3 | 0.441 |
| PT (seconds) | 12.0 ± 0.8 | 12.0 ± 0.9 | 12.0 ± 0.6 | 0.982 |
| APTT (seconds) | 35.0 ± 10.7 | 35.6 ± 11.6 | 31.8 ± 2.7 | 0.239 |
| Liver function index | ||||
| Aspartate aminotransferase (U/L) | 32.5 ± 16.0 | 32.4 ± 15.7 | 32.7 ± 20.2 | 0.981 |
| Alanine aminotransferase (U/L) | 43.7 ± 35.8 | 44.3 ± 37.8 | 40.9 ± 28.0 | 0.866 |
| Total bilirubin (μmol/L) | 11.0 ± 3.4 | 10.9 ± 3.3 | 11.6 ± 4.3 | 0.703 |
| Direct bilirubin (μmol/L) | 3.7 ± 1.3 | 3.6 ± 1.2 | 3.9 ± 1.8 | 0.691 |
| Lactic dehydrogenase (U/L) | 241.1 ± 72.0 | 254.6 ± 71.6 | 177.1 ± 25.0 | 0.048 |
| Kidney function index | ||||
| Blood urea nitrogen (mmol/L) | 5.1 ± 1.0 | 5.1 ± 1.0 | 5.0 ± 1.6 | 0.885 |
| Serum creatinine(μmol/L) | 70.6 ± 12.8 | 70.9 ± 12.9 | 69.2 ± 14.0 | 0.821 |
| K+ (mmol/L) | 3.2 ± 0.3 | 3.2 ± 0.3 | 3.2 ± 0.2 | 0.953 |
| Na+ (mmol/L) | 141.9 ± 1.3 | 141.9 ± 1.2 | 141.8 ± 1.8 | 0.828 |
| CRP (mg/L) | 16.2 ± 25.0 | 14.7 ± 21.2 | 23.3 ± 42.5 | 0.465 |
| SAA(mg/L) | 63.2 ± 93.1 | 67.4 ± 98.4 | 42.8 ± 69.6 | 0.641 |
| Pneumonia index | 136.7 ± 166.6 | 145.8 ± 174.9 | 93.5 ± 130.5 | 0.581 |
BMI: body mass index; COVID-19: coronavirus disease 2019; DBP: diastolic blood pressure; SBP: systolic blood pressure; SD: standard deviation; VTE: venous thromboembolism; PT:Prothrombin time; APTT:Activated partial thromboplastin time; CRP: C-reactive protein; SAA: serum amyloid A.