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. 2020 Dec 13;2(2):fcaa191. doi: 10.1093/braincomms/fcaa191

Figure 1.

Figure 1

Immunotherapy and electrical myotonia and fibrillations in IMNM. IMNM patients (n = 19) undergoing serial EMGs pre-immunotherapy and at last treatment follow-up. Myotonic discharges and fibrillations reduce in frequency while on immunotherapy. On initial pre-treatment EMG Case 3 had electrical myotonia identified in both lumbar and thoracic paraspinal muscles and in Case 13 electrical myotonia was also identified in the infraspinatus muscle. On follow-up post treatment EMG Case 4 also had electrical myotonia identified in the infraspinatus muscle. Electrical myotonia resolution correlated better to treatment response than fibrillation resolution. IMNM = immune-mediated necrotizing myopathy; FDI = first dorsal interossei; Hip girdle = gluteus maximus, gluteus medius, iliopsoas or tensor fascia lata.