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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Brain Behav Immun. 2020 Oct 8;91:296–314. doi: 10.1016/j.bbi.2020.10.008

Fig. 7.

Fig. 7.

Intracerebroventricular α2 adrenoceptor antagonist (atipamezole) reduced dexmedetomidine protection on sepsis-induced systemic inflammation and neuroinflammation. (A) Representative immunofluorescent images. Scale bar = 100 μm in the upper panel and = 50 μm in the lower panel. (B) Quantitative results of the percentage of Iba-1 positive area in the total area of the image in the hippocampus. (C) C3 concentration in the hippocampus. (D) Concentrations of TNF-α, IL-6 and IL-1β in the serum and hippocampus. All results are expressed as mean ± S.D. (n = 6 in each group). Each animal data point in the bar graph is also presented. ATI: atipamezole, Dex: dexmedetomidine.