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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Brain Behav Immun. 2020 Oct 8;91:296–314. doi: 10.1016/j.bbi.2020.10.008

Fig. 8.

Fig. 8.

Intracerebroventricular α2 adrenoceptor antagonist (yohimbine) reduced dexmedetomidine protection on sepsis-impaired learning and memory in mice. (A) Training sessions of Barnes maze. (B) Memory phase of Barnes maze. (C) Context- and tone-related fear conditioning test. All results are expressed as mean ± S.D. (n = 11 – 12 in each group for panels A to C). Each data point in the bar graph is also presented. * P < 0.05 compared with the corresponding data on day 1. Dex: dexmedetomidine, Yoh: yohimbine.