Skip to main content
. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: J Hepatol. 2020 Aug 4;74(1):156–167. doi: 10.1016/j.jhep.2020.07.041

Figure 5. Hepatocyte-specific Nlrp3 mutant mice are more prone to LPS- induced liver inflammation and hepatocytes cell death.

Figure 5.

(A) H&E staining, (B) TUNEL positive cells (% of total area), (C) F4/80 positive cells and (D) Cd11b positive cells (% of total cells) in livers from WT and Nlrp3KICreA mice injected with LPS (scale bars: 200 μm). (E) Western blot and densitometric analysis of GasderminD N-terminal (31 kDa) protein in liver lysate from WT (n=3) and Nlrp3KICreA mice (n=3) injected with LPS. Data were normalized on β-actin. Two groups were analyzed by Studentś T-tes (*p< 0.05 vs. WT control).