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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: J Hepatol. 2020 Jul 11;74(1):48–57. doi: 10.1016/j.jhep.2020.06.044

Figure 2. In AIH Treg and Th17-cells display defective ADPase and AMPase activity upon exposure to AHR ligands.

Figure 2.

Mean+SEM (A-B) ADP/AMP ratio and (C-D) AMP/adenosine ratio in untreated, UCB, L-Kynurenine and quercetin-treated Treg and Th17-cells 5, 10, 20, 40 minutes after addition of 14C-labelled ADP (HS, n=4; AIH, n=4). (E) Mean+SEM % inhibition of CD4+CD25−-cell proliferation in the presence of untreated or treated Treg is shown (HS, n=8; AIH, n=10). *P≤0.05; **P≤0.01; ***P≤0.001 (one-way ANOVA).