Table 5.
Sleepiness in Subjects With Vs. Without PLMS Stratified by RLS Symptom Status
| RLS Symptoms Positive | PLMI <15† | PLMI ≥15† | |
|---|---|---|---|
| Subjects/ Observations (368/829) | 499 observations (n=234) | 330 observations (n=134) | |
| Characteristic | mean ± SE | mean ± SE | p-value |
| MSLT mean (305/600) | 11.4 ± 0.4 | 10.3 ± 0.4 | p=0.0077 |
| Epworth mean (367/828) | 9.1 ± 0.4 | 9.8 ± 0.4 | p=0.0030 |
| Characteristic | Odds Ratio (95% CI)† | ||
| MSLT <8 (305/600) | 1.87 (1.22-2.86) | ||
| Epworth >10 (367/828) | 1.17 (0.88 - 1.54) | ||
| EDS | 2.17 (1.47 - 3.12) | ||
| RLS Symptoms Negative | PLMI <15† | PLMI ≥15† | |
| Subjects/ Observations (513/1120) | 818 observations (n=400) | 302 observations (n=113) | |
| Characteristic | mean ± SE | mean ± SE | p-value |
| MSLT mean (398/765) | 11.7 ± 0.4 | 12.2± 0.4 | p=0.1604 |
| Epworth mean (512/1119) | 8.8 ± 0.3 | 8.9 ± 0.4 | p=0.925 |
| Characteristic | Odds Ratio (95% CI)† | ||
| MSLT <8 (398/765) | 0.70 (0.50 - 1.10) | ||
| Epworth >10 (512/1119) | 1.03 (0.77 - 1.39) | ||
| EDS | 0.89 (0.59 - 1.34) | ||
Reported mean ± standard error (SE) based on observations, not subjects. p-values based on F statistic.
†
Adjusted for age, gender, depression, habitual sleep time, insomnia, total sleep time, sleep efficiency, cardiovascular disease. PLMI, periodic limb movement index based Stanford’s PLM detector; RLS, restless legs syndrome symptoms (as described in Methods Section); MSLT, multiple sleep latency test; EDS, excessive daytime sleepiness (as described in Methods Section).