Fig. 2.

Nonspecific interstitial pneumonia in a 48-year-old woman with dermatomyositis. (a, b) Lung window images of CT scans obtained at levels of right inferior pulmonary vein (a) and liver dome (b), respectively, show reticulation and traction bronchiectasis (arrowheads) in both lungs with lower lung zone predominance. (c) Low power magnification, and medium power magnification (inset) of lung demonstrates temporally uniform diffuse parenchymal fibrosis typical of fibrotic NSIP. Superimposed are diffusely scattered lymphoid follicles containing reactive germinal centers, which suggest CTD as the underlying cause of the fibrotic NSIP but are not specific. (d, e). Ten-year follow-up CT scans obtained at similar levels to a & b, respectively, depict progression of pulmonary fibrosis with apparent areas of traction bronchiectasis in both lungs.