Table 1.

Baseline characteristics of MESA participants according to Lp(a) levels^*

Characteristic	Lp(a) <50 mg/dL (n=5359)	Lp(a) ≥50 mg/dL (n=1346)	p-value†
Age	62.0 (10.3)	62.4 (10.0)	0.27
Male, %	2614 (48.8%)	550 (40.9%)	<0.001
Race, %
White	2169 (40.5%)	413 (30.7%)	<0.001
Chinese	718 (13.4%)	75 (5.6%)
African-American	1207 (22.5%)	641 (47.6%)
Hispanic	1265 (23.6%)	217 (16.1%)
Education, %
High school or less	1946	482	0.65
Some college	1503	394
College or more	1893	464
Body mass index, kg/m2	28.2 (5.4)	28.8 (5.7)	<0.001
Family history of MI,	2106 (41.8%)	583 (46.3%)	0.004
Hypertension, %	2328 (43.4%)	670 (49.8%)	<0.001
Systolic blood pressure, mmHg	126.0 (21.3)	128.2 (22.1)	0.001
Diastolic blood pressure, mmHg	71.7 (10.2)	72.4 (10.4)	0.023
Total cholesterol, mg/dL	191.7 (35.1)	203.1 (36.6)	<0.001
HDL cholesterol, mg/dL	114.8 (30.8)	126.1 (32.1)	<0.001
Glucose, mg/dL	97.5 (30.4)	96.6 (29.4)	0.32
Diabetes, %	649 (12.1%)	193 (14.4%)	0.007
Smoking status, %
Never	2688 (50.3%)	675 (50.4%)	0.17
Former	1980 (37.1%)	472 (35.2%)
Current	675 (12.6%)	193 (14.4%)
hs-CRP, mg/dL	3.7 (5.8)	4.2 (6.4)	0.008
eGFR	81.3 (18.5)	80.7 (18.3)	0.22
Anti-hypertensive use, %	1927 (36.0%)	560 (41.6%)	<0.001
Statin use, %	1078 (18.9%)	267 (27.0%)	<0.001
Aspirin use, %	1669 (31.2%)	449 (33.4%)	0.12
Coronary artery calcium score	140.9 (394.4)	164.8 (499.7)	0.060
Mitral annular calcium score	48.8 (438.0)	48.7 (386.7)	1.00
Thoracic aortic calcium score	220.3 (871.5)	204.2 (836.3)	0.54

MI=myocardial infarction; HDL=high-density lipoprotein

^*Continuous variables are expressed as mean (SD). Categorical variables are N (percent).

^†Comparisons were made between Lp(a)<50 mg/dL and Lp(a) ≥50 mg/dL. Fisher’s exact used to make statistical comparison.