Table 3.
ROIs pair | anatomical WM fibers | TD-N | PIGD-N | p value |
---|---|---|---|---|
MD (10−3 mm2/s) | ||||
lh-superior temporal gyrus__lh-insula | left superior longitudinal fasciculi | 0.775 ± 0.023 | 0.758 ± 0.040 | 0.005 |
rh-pars opercularis gyrus__rh-insula | right fronto-insular tracts | 0.740 ± 0.022 | 0.750 ± 0.031 | 0.004 |
RD (10−3 mm2/s) | ||||
lh-superior temporal gyrus__lh-insula | left superior longitudinal fasciculi | 0.603 ± 0.024 | 0.605 ± 0.036 | 0.005 |
rh-inferior temporal gyrus__rh-middle temporal gyrus | right temporal U-fibers | 0.602 ± 0.019 | 0.599 ± 0.029 | 0.01 |
rh-pars opercularis__rh-insula | right fronto-insular tracts | 0.589 ± 0.025 | 0.598 ± 0.035 | 0.003 |
rh-pars opercularis__rh-pars triangularis | right frontal U-fibers | 0.588 ± 0.024 | 0.607 ± 0.064 | 0.01 |
Note: values are expressed as mean ± standard deviation. rh = right hemisphere. lh = left hemisphere. The ANCOVA was performed with subjects’ age, years of disease duration, FAS verbal fluency task scores as covariates.