Table 4.
Effects of FAS verbal fluency scores in the whole brain network for the PD-N cohort: MD results.
| ROIs pair | MD (10−3 mm2/s) | p value |
|---|---|---|
| Cortical regions | ||
| Frontal cortex | ||
| rh-caudal middle frontal gyrus__rh-superior frontal gyrus | 0.737 ± 0.030 | 0.011 |
| rh-caudal middle frontal gyrus__rh-precentral cortex | 0.730 ± 0.025 | 0.015 |
| rh-pars triangularis__rh-rostral middle frontal gyrus | 0.757 ± 0.053 | 0.034 |
| rh-medial orbitofrontal cortex__rh-rostral anterior cingulate cortex | 0.804 ± 0.038 | 0.024 |
| Temporal cortex | ||
| rh-inferior temporal gyrus__rh-insula | 0.781 ± 0.031 | 0.045 |
| rh-inferior temporal gyrus__rh-superior temporal gyrus | 0.768 ± 0.026 | 0.036 |
| Parietal cortex | ||
| rh-superior parietal cortex__rh-supramarginal gyrus | 0.767 ± 0.037 | 0.037 |
| Occipital cortex | ||
| lh-cuneus cortex__lh-pericalcarine cortex | 0.780 ± 0.040 | 0.028 |
| Fronto-temporal cortex | ||
| rh-pars triangularis__rh-insula | 0.745 ± 0.024 | 0.018 |
| rh-precentral cortex__rh-insula | 0.742 ± 0.030 | 0.012 |
| Fronto-parietal cortex | ||
| rh-postcentral cortex__rh-precentral cortex | 0.753 ± 0.030 | 0.023 |
| lh-precentral cortex__lh-superior parietal cortex | 0.734 ± 0.028 | 0.037 |
| Temporo-parietal cortex | ||
| rh-postcentral cortex__rh-insula | 0.76 ± 0.0370 | 0.048 |
| rh-supramarginal gyrus__rh-insula | 0.756 ± 0.031 | 0.042 |
| Parieto-occipital cortex | ||
| lh-pericalcarine cortex__lh-precuneus cortex | 0.805 ± 0.041 | 0.047 |
| rh-cuneus cortex__rh-precuneus cortex | 0.765 ± 0.035 | 0.021 |
| rh-fusiform gyrus__rh-para hippocampal gyrus | 0.832 ± 0.115 | 0.049 |
| Cortico-subcortical regions | ||
| lh-Pallidum__lh-insula cortex | 0.731 ± 0.051 | 0.044 |
Note: values are expressed as mean ± standard deviation. rh: right hemisphere. lh: left hemisphere. Age, years of duration, and phenotype were defined as covariates in the ANCOVA model.