Fig. 5.

Effect of INAE on liver, thymus and spleen. Mice were infected with 3 × LD₅₀ of IAV and administered orally with INAE, ribavirin or 0.5% CMC-Na at indicated doses once daily for 4 days. Weights of liver, thymus and spleen were measured and calculated (a, b). Serum ALT and AST levels were evaluated (c). Organ index = Organ weight / body weight × 100%. Data were presented as mean ± S.D. (n = 6). ^* P < 0.05, **P < 0.01, ***P < 0.001 compared with model group, tested by ANOVA and Fisher’s PLSD