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. 2020 Dec 7;10:538336. doi: 10.3389/fcimb.2020.538336

Table 1.

Comparison of patient age, HPV infection status and TCT test results.

Variable C Group (N = 27) CIN Group (N = 22) CER Group (N = 23) P value
Percentage of total enrollment, 27(37.5) 22(30.56) 23(31.94) /
No (%).
Age (mean ± std. deviation) 34.04 ± 3.142 35.53 ± 2.951 34.16 ± 1.914 0.1374
TCT result category, No (%). <0.0001
NILM 27 (100%) 9 (40.91%) 1 (4.34%)
LSIL 0 (0%) 3 (13.63%) 2 (8.69%)
HSIL 0 (0%) 5 (22.73%) 9 (39.14%)
ASC 0 (0%) 5 (22.73%) 7 (30.44%)
Squamous cell carcinoma 0 (0%) 0 (0%) 4 (17.39%)
HPV infection subtype, No (%). <0.0001
Negative 27(100%) 2(9.09%) 1(4.35%)
16 or 18 0(0%) 13(59.09%) 19(82.61%)
Others 0(0%) 7(31.82%) 3(13.04%)

Age differences between groups are not statistically significant (P = 0.1347). The rates of high-risk HPV infection and abnormal rates of TCT in the CER and CIN groups were higher than those in the C group (P<0.0001). P value less than 0.05 is statistically significant.

C group, healthy control group; CIN group, Cervical intraepithelial neoplasis group; CER group, Cervical cancer group; NILM, No intraepithelial lesions and malignant lesions; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; ASC, atypical squamous cell.