Table 2.

Binding energies of drugs using PyRx docking software.

NSPs	Drug_ID	DB00150	DB01977	DB02441	DB03225	DB03314	DB07132	DB07535	DB08136	DB08466	DB12291
NSP 3	Binding energy in Kcal/mol of 6wuu	−6.4	−8.4	−7.3	−6.3	−6.7	−8.3	−8.2	−7.6	−7.1	−7.5
NSP 5	Binding energy in Kcal/mol of 6wuu	−7.3	−9.2	−6.6	−7.3	−7.2	−9	−8.2	−7.7	−7.2	−8.4
	Binding energy in Kcal/mol of 6wuu	−7.1	−8.2	−6.9	−7	−6.7	−7.5	−8.6	−7.7	−7.2	−7.4
NSP 10	Binding energy in Kcal/mol of 6wuu	−6.1	−7.1	−6	−6.1		−7	−7.2	−6.9	−6.5	−6.3
NSP 11	Binding energy in Kcal/mol of 6wuu	−6	−7.7	−7	−6.1	−6.3	−7.3	−7.5	−7.2	−6.2	−6.9
	Binding energy in Kcal/mol of 6wuu	−6.8	−8	−6.7	−6.8	−6.6	−7.3	−7.5	−7.3	−7	−7.2
NSP 14	Binding energy in Kcal/mol of 6wuu	−7	−8.8	−6.9	−7	−7.2	−8	−8.6	−7.9	−7.2	−7.8
	Binding energy in Kcal/mol of 6wuu	−7.2	−8.1	−7.2	−7.6	−7.6	−7.1	−8	−7.1	−7	−8.3
	Binding energy in Kcal/mol of 6wuu	−7.1	−8.1	−7.3	−7.1	−7.3	−7.8	−8.2	−7.8	−7	−8.2
	Binding energy in Kcal/mol of 6wuu	−7	−7.8	−6.9	−7.1	−7.1	−7.8	−7.3	−7.2	−6.9	−7.9
	Binding energy in Kcal/mol of 6wuu	−7.1	−7.8	−6.9	−7.1	−7.2	−8.2	−7.6	−7.3	−7.2	−7.7
	Binding energy in Kcal/mol of 6wuu	−7.4	−8.1	−6.9	−7.3	−7.5	−7.9	−7.8	−7.2	−7.5	−7.8
	Binding energy in Kcal/mol of 6wuu	−7.2	−7.9	−7	−7.2	−7.4	−8.4	−7.9	−7.4	−7.4	−7.8
	Binding energy in Kcal/mol of 6wuu	−7.1	−7.9	−6.9	−7.1	−7.3	−8	−7.8	−7.3	−7.3	−7.8
	Binding energy in Kcal/mol of 6wuu	−7.1	−7.9	−7	−7.1	−7.3	−8.1	−7.8	−7.2	−7.3	−7.8
NSP 15	Binding energy in Kcal/mol of 6wuu	−6.7	−8.2	−6.6	−6.7	−7.1	−8	−8.3	−7.6	−6.9	−7.6
	Binding energy in Kcal/mol of 6wuu	−7	−8.3	−6.6	−7	−6.9	−7.4	−8.2	−7.5	−7.1	−7.5
	Binding energy in Kcal/mol of 6wuu	−6.9	−7.5	−6.6	−6.9	−7	−8.5	−7.9	−7	−6.9	−6.8

Note: The binding energy given above are for the poses with RMSD = 0.