Skip to main content
. 2020 Dec 17;27:33–43. doi: 10.1016/j.jot.2020.09.006

Figure 4.

Figure 4

Erastin promoted matrix metalloproteinase 13 (MMP13) expression while inhibited Type II collagen (collagen II) expression in chondrocytes (A) The protein expression level of GPX4, collagen II and MMP13 when treated with erastin were detected by western blot (B) The band density ratio of GPX4, collagen II and MMP13 to β-actin in the western blots were quantified by densitometry (C) The protein expression level of collagen II and MMP13 when treated by IL-1β with 1 μM ferrostain-1 or equal volume of DMSO were detected by western blot (D-E) The band density ratio of collagen II and MMP13 to β-actin in the western blots were quantified by densitometry (F) The protein expression level of collagen II and MMP13 when treated by FAC with 1 μM ferrostain-1 or equal volume of DMSO were detected by western blot (G-H) The band density ratio of collagen II and MMP13 to β-actin in the western blots were quantified by densitometry.∗P < 0.05 versus control, #P < 0.05 versus IL-1β or FAC treated group. Ns P > 0.05 versus IL-1β or FAC treated group. Error bars represent SD.