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. 2020 Dec 7;8:586874. doi: 10.3389/fbioe.2020.586874

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Copyright © 2020 Jin, Chang, Dou, Jin, Jiao, Tang, Jiang, Ren and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FUS-triggered DOX release from MF-MNB. (A) Drug release rate depends on different FUS sonication powers of 0.4, 0.6, 0.8, 1.0, and 1.2 MPa. (B) Time-dependent DOX release profile with/without FUS sonication (*p < 0.05, **p < 0.01).