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. 2020 Dec 7;8:586874. doi: 10.3389/fbioe.2020.586874

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Copyright © 2020 Jin, Chang, Dou, Jin, Jiao, Tang, Jiang, Ren and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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US and MR image of MF-MNB. (A,B) US image and US signal intensity of (a) air, (b and c) 100 mg/ml and 200 mg/ml of MF-MNB without SPIO loading, (d to h) 200 mg/ml of MF-MNB with different SPIO weight percent of 5.7, 12.1, 17.6, 25.4, and 31.2, and (i) degassed and deionized water. (C) T₂-weighted MR image of MF-NRS in aqueous solution at different Fe concentration. (D) Relaxation rate r2 (1/T₂) of MF-NRS at different as a function of Fe concentrations.