Table 3B.

Response to applied therapy in two adult/one mixed and in our cohort.

Study	Pyridostigmine	3,4 Diaminopyridine	Acetazolamide	Albuterol/Salbutamole	Ephedrine	Fluoxetine	Chinidine
Natera-de Benito et al. (2017)	↑CHRNE, RAPSN	↑CHRNE, RAPSN, DOK7	-	↑CHAT, COLQ, DOK7, slow channel	↑CHAT, COLQ, DOK7, slow channel	slow channel	-
Durmus et al. (2018)	↑CHAT, CHRNE, slow channel(short), fast channel ↓ DOK7	-	-	↑CHAT, DOK7, slow channel	-	↑slow channel	-
Kao et al. (2018)	↑CHRNE, DOK7, RAPSN ↓DOK7, slow channel	↑CHRNE, DOK7, RAPSN ↓DOK7	↑ RAPSN	↑COLQ, CHRNE, DOK7, RAPSN	↑DOK7, RAPSN	↑slow channel	-
Our cohort	↑CHAT, CHRNE, RAPSN, fast channel ↓COLQ, DOK7	↑CHAT, CHRNE, fast channel	-	-	↑COLQ, DOK7	-	↑slow channel

Nr., number; pat., patients; supp., support; ↑, improvement;↓, worsening.