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. 2020 Dec 7;11:606497. doi: 10.3389/fphar.2020.606497

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Copyright © 2020 Su, Li, He, Zhao, Wan, Liu, Xu, Xu, Liu, Jiang, Wu, Zuo, Huang, Liu, Li, Zhang, Liu, Dong, Li, Chen, Li, He, Lu, Huang, Tao, Wang, Zhang, Wei, Li and Zeng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Total back pain, (B) nocturnal back pain, (C) swollen joint count, (D) MASES, (E) PaGA, (F) PhGA, and (G) BASDAI values at each time point during the 24-week treatment period in patients treated with HS016 or adalimumab. *p < 0.05, compared with baseline in the HS016 group; ^# p < 0.05, compared with baseline in the adalimumab group. BASDAI, Bath ankylosing spondylitis disease activity index; MASES, Maastricht ankylosing spondylitis enthesitis score; PaGA, Patient global assessment; PhGA, Physician global assessment; SJC, swollen joint count.