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. 2020 Dec 18;12:1758835920974192. doi: 10.1177/1758835920974192

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© The Author(s), 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Monitoring of the EGFR^activating and EGFR^T790M alterations in circulating tumor DNA (ctDNA) samples collected before and after histological transformation. The levels of the EGFR^del19 or EGFR^L858R (blue line) and EGFR^T790M (red line) mutations (copies/ml of plasma) were measured by droplet digital PCR. Asterisks indicated ctDNA samples analyzed by NGS.

LC, lung carcinoma; NGS, next-generation sequencing; SCLC, small cell lung cancer.