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Molecular alterations detected by NSG in liquid biopsy samples collected before (yellow) and after histological transformation (green). The number in the boxes corresponds to the variant allele fraction of the mutation or the gene copy number for amplifications. Samples were analyzed using the LiquidPlex™ 28-Gene Kit (ArcherDx) and sequenced on a NextSeq platform (Illumina).
LC, lung carcinoma; NGS, next-generation sequencing.
