TABLE 1.
Cluster (Isolates) | Variant loci1 | Non-synon (Ka) | Synon (Ks) | Ka:Ks Ratio | Recombination fragments2 | Recombinant loci3 |
A (15) | 90 | 61 | 29 | 2.10 | 10 | 21 |
B (5) | 6 | 4 | 2 | 2.00 | 0 | 9 |
C (6) | 18 | 9 | 9 | 1.00 | 0 | 18 |
D (7) | 15 | 11 | 4 | 2.75 | 0 | 6 |
E (5) | 8 | 7 | 1 | 7 | 0 | 0 |
F (8) | 270 | 98 | 172 | 0.57 | 17 | 69 |
G (6) | 48 | 16 | 32 | 0.5 | 0 | 25 |
Total | 455 | 206 | 249 | 0.8 | 27 | 148 |
1Variant loci were identified by analysis of 3,034 loci defined in the Neisseria PubMLST genome repository and are defined as having one variant nucleotide relative to the consensus sequence of all isolates within a cluster. 2Recombination fragments were predicted using RDP4. 3Recombinant loci, loci where one or more alleles contained > 1 variant nucleotides relative to the consensus of all alleles within a cluster.