In vivo antitumor efficacy after the treatment. The changes in body weight (A) and tumor weight (B) from H22 tumor-bearing Kunming mice treated with saline (a), free ASODN (b), DGL-ASODN (c), DGL-FA-ASODN (d), DGL-FA-ASODN-DCA (e), and GEL-DGL-FA-ASODN-DCA (f) with a dosage of 5 mg ASODN per kg BW by tail vein injection every other day for 14 d, respectively. (C) The photograph of the tumors separated from these mice. The scale bar in figure shows 3 cm. The data are expressed as mean ± SD (n = 7). *P < 0.05 versus control group according to ANOVA.