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. 2020 Dec 17;19:1533033820973270. doi: 10.1177/1533033820973270

Table 1.

DEGs in the Rectal Cancer Tissues Compared to Normal Tissues.

DEGs Gene names
Upregulated DEGs ABCC1, ALDOB, ANLN, APOBEC1, AQP9, ARG2, ARID3A, ASPM, AXIN2, AZGP1, BOP1, BUB1, C4BPA, CA9, CCNB1, CDC25B, CDCA7, CDH3, CDK4, CEBPB, CELSR3, CENPA, CENPF, CGREF1, CHI3L1, CKS2, CLDN1, COL4A1, COL7A1, COL8A1, CSE1L, CST1, CTHRC1, CXCL1, CXCL11, CXCL2, CXCL3, CXCL5, CXCL6, CYP4X1, DACH1, DDIT4, DEFA6, DKC1, DPEP1, DUSP14, DUSP4, EDNRA, EGFL6, ESM1, ETV4, FABP6, FAM19A5, FAM3B, FANCB, FAP, GDF15, GPSM2, GPT2, GTF2IRD1, GZMB, HOMER1, HTRA3, IFITM1, IFITM3, IL11, IL13RA2, IL23A, INHBA, INHBB, JAG2, KHK, KLK10, KRT17, KRT23, LRP8, MCM4, MEST, MFAP2, MMP11, MMP12, MMP3, MMP7, MTHFD1L, MYBL2, NEBL, NFE2L3, NMB, OSM, PHLDA1, PITX2, PRC1, PROX1, PSAT1, PTP4A3, PTTG1, RAD54L, REG1A, REG3A, RFC3, RGS16, RIPK2, RNASEH2A, RPP40, S100A2, S100A9, SAA1, SAA2, SERPINE2, SLC22A3, SLC39A10, SLC5A6, SLC6A20, SLCO4A1, SNTB1, SOX9, STRA6, SULF1, SULT2B1, TACSTD2, TCN1, TDGF1, TDO2, TGFBI, THBS2, TNFRSF10C, TOMM34, TOP1MT, TOP2A, TPX2, TRAP1, TRIB3, TRIP13, TTK, TYRO3, UBD, UBE2C, UBE2S, VSNL1, WNT2, WNT5A, XPOT
Downregulated DEGs ABCA8, ABCG2, ABHD3, ACADS, ACAT1, ACVRL1, ADAMDEC1, ADH1C, AKAP7, AKR1B10, AMPD1, ANGPTL1, AOC3, AQP8, ATP2A3, B3GALT5, BCAR3, BCAS1, BMP6, BTNL8, C7, CA1, CA12, CA2, CA4, CA7, CAPN13, CBLN2, CCL19, CD36, CD79A, CDH19, CDKN2B, CEACAM7, CES2, CHGA, CHGB, CHST5, CILP, CKB, CLCA4, CLDN23, CLDN8, CLEC10A, CLEC3B, CLIC5, CLMN, CLU, CPB1, CPM, CPNE5, CPNE8, CR2, CRYBA2, DEFB1, DHRS9, DISP2, DNASE1L3, DSC2, EAF2, EDN3, EFEMP1, ENTPD5, ENTPD8, EPB41L3, ETHE1, F13A1, FABP1, FABP2, FAM3D, FCGBP, FEV, FGFBP1, FGL2, FHL1, FMN2, FMO5, FOLR2, FUCA1, FXYD3, GALNT12, GCG, GCNT3, GDPD2, GHR, GLTP, GNE, GNG7, GP2, GPA33, GPM6B, GPT, GREM2, GSN, GUCA2A, HGD, HHLA2, HIST1H1C, HOXD10, HOXD11, HPGD, HRASLS2, HSD11B2, HSD17B2, IL1R2, IL6R, INSL5, IQGAP2, ITLN1, ITM2A, ITM2C, ITPKA, JAM2, KLK1, KRT20, KRTAP13-2, LDHD, LGALS2, LGALS4, LGI1, LGI4, LIPH, LMOD1, LRRC19, LTK, MAL, MAOA, MATN2, MEP1A, MMP28, MS4A12, MT1E, MT1F, MT1G, MT1H, MT1X, MTM1, MXI1, MYO1A, NAP1L2, NEDD4L, NEU4, NEUROD1, NPY, NR3C1, NR3C2, OGN, P2RY14, PAPSS2, PCSK5, PDCD4, PDE6A, PDE9A, PDGFD, PINK1, PKIB, PLA2G10, PLAC8, PLCD1, PLCG2, PLCL2, PLS1, POU2AF1, PPARGC1A, PPP2R3A, PRDX6, PRKACB, PTN, PTPRH, PYY, RAB37, RDH5, RHBDL2, RIOK3, ROR1, SAMD9, SCG2, SCGB2A1, SCGN, SCIN, SCN4B, SCNN1B, SDCBP2, SELENBP1, SEMA6A, SFRP1, SIDT1, SLC17A4, SLC22A5, SLC25A20, SLC26A2, SLC26A3, SLC30A10, SLC4A4, SLCO2A1, SMPD1, SMPDL3A, SPDEF, SPIB, SPINK2, SPINK5, SPPL2A, SRI, SRPX, SSPN, SST, ST6GALNAC6, STMN2, STYK1, SULT1A2, SYTL2, TBX10, TMCC3, TMPRSS2, TNFRSF17, TRIM36, TRPM6, TSLP, TSPAN1, TUBAL3, TXNIP, UGDH, UGP2, UGT1A8, UGT2B17, VLDLR, VPREB3, VSIG2, ZZEF1

Note: A total of 142 genes were significantly upregulated and 229 genes were significantly downregulated in TCGA database, GSE15781 and GSE20842.

Abbreviations: DEG, differentially expressed genes.