Table 2.

Patient and Caregiver Cost of Illness Due to Enteric Fever: Direct Medical, Direct Nonmedical, Indirect, and Total Costs, Karachi, Pakistan, September 2016–December 2018

	Patients Who Only Reported Outpatient Care Expenses and did not Have a Nontraumatic Terminal Ileal Perforationa				Patients Who Reported Inpatient Care Expenses or Had a Nontraumatic Terminal Ileal Perforationb				All Patients
Cost Type	n	Median	25th Pctl	75th Pctl	n	Median	25th Pctl	75th Pctl	n	Median	25th Pctl	75th Pctl
Direct medical costs, 2018 US$
Total direct medical costs	834	126.27	47.04	374.56	146	235.85	115.25	456.06	980	145.98	53.51	387.73
Registration	399	4.12	2.14	17.11	51	4.28	1.71	16.46	450	4.12	2.06	16.46
Clinical examination	25	4.12	1.65	6.84	21	10.70	4.12	16.46	46	5.14	2.88	11.55
Inpatient stay	0	N/A	N/A	N/A	27	74.09	23.09	179.62	27	74.09	23.09	179.62
Laboratory tests	203	25.66	10.70	49.39	51	32.93	8.23	82.32	254	25.66	10.26	51.86
Drugs and medications	371	12.83	6.84	41.16	90	32.93	10.26	82.32	461	16.46	7.00	49.39
Other servicesc	8	8.42	3.34	13.26	36	25.18	10.45	48.57	44	23.04	8.23	41.16
Direct nonmedical costs, 2018 US$
Total direct nonmedical costs	694	4.57	2.47	10.26	138	36.86	9.06	115.25	832	5.35	2.63	16.46
Transport	691	4.28	2.47	8.55	138	18.86	8.23	57.63	829	5.13	2.57	12.35
Food, lodging, childcare	76	32.93	16.46	82.32	68	49.39	31.28	90.55	144	41.16	21.38	83.93
Direct medical and nonmedical expenses, 2018 US$
Direct medical and nonmedical preenrollment expenses	591	21.38	7.41	53.51	120	53.03	16.79	141.69	711	24.70	8.23	76.55
Total direct medical and nonmedical expenses	859	129.24	48.57	384.89	147	316.94	196.72	605.40	1006	162.59	57.79	419.84
Indirect costs: patient
Days spent seeking care	868	1.32	0.13	4.00	149	9.00	6.00	15.00	1017	3.00	0.17	6.00
Days unable to work	27	14.00	4.00	48.00	42	58.50	30.00	85.00	69	35.00	14.00	60.00
Days of sick leave	51	14.00	7.00	28.00	4	40.00	15.00	135.00	55	15.00	7.00	28.00
School days lost	399	30.00	15.00	46.00	44	67.50	30.00	120.00	443	30.00	15.00	50.00
Total productivity loss, 2018 US$	74	96.30	46.38	198.61	42	327.71	173.91	498.07	116	147.43	68.79	287.99
Indirect costs: caregiver
Days spent accompanying the patient seeking care	849	3.31	0.33	9.00	148	19.00	11.01	33.50	997	5.00	0.42	12.00
Days unable to work	167	5.00	2.00	12.00	107	15.00	8.00	30.00	274	9.00	3.00	17.00
Days of sick leave	217	3.00	1.33	6.00	14	6.50	3.00	20.00	231	3.00	2.00	6.00
Total productivity loss, 2018 US$	373	21.24	13.24	49.74	116	92.69	47.25	173.91	489	30.19	13.24	79.44
Cost of illness, 2018 US$
Total cost of illness per case	863	149.11	60.23	424.31	148	476.12	250.26	983.85	1011	196.37	72.89	496.40
Total cost of illness per case without the value of sick leave	859	140.77	51.55	409.55	147	471.13	250.26	978.30	1006	175.15	64.15	484.11

N = 1029.

Abbreviations: N/A, not applicable because it excludes inpatient care; Pctl, percentile.

^a Expenses by patients who only reported outpatient care, regardless of patient recruitment location (outpatient care, inpatient care, hospital laboratory, surgery) and excluding patients with nontraumatic terminal ileal perforation.

^b Expenses by patients with nontraumatic terminal ileal perforation, regardless of whether they reported inpatient care, and patients reporting inpatient care expenses, regardless of patient recruitment location (outpatient care, inpatient care, hospital laboratory, surgery).

^c Other services that patients did not report in the above categories (eg, medical materials or equipment for surgery).