Table 3.

Sensitivity Analysis of Patient and Caregiver Cost of Illness Due to Enteric Fever: Direct Medical, Direct Nonmedical, Indirect, and Total Costs When Excluding Outliers—Nepal, September 2016–December 2018

	Patients Who Did Not Report Any Inpatient Care Expensesa				Patients Who Reported Inpatient Care Expensesa				All Patients
Cost Type	n	Median	25th Pctl	75th Pctl	n	Median	25th Pctl	75th Pctl	n	Median	25th Pctl	75th Pctl
Direct medical costs, 2018 US $
Total direct medical costs	275	24.86	14.59	43.54	98	138.45	95.73	204.00	373	34.19	18.23	91.17
Registration	247	0.73	0.64	1.28	75	1.09	0.64	1.82	322	0.73	0.64	1.37
Clinical examination	10	1.54	0.39	3.28	3	1.82	0.46	3.32	13	1.82	0.46	3.28
Inpatient stay	0	N/A	N/A	N/A	93	12.34	7.29	23.71	93	12.34	7.29	23.71
Laboratory tests	227	13.68	6.38	20.70	71	31.17	18.04	42.85	298	15.33	8.94	27.44
Drugs and medications	251	7.84	4.31	11.67	83	43.76	18.23	75.91	334	9.30	4.89	21.43
Other servicesb	2	8.25	3.68	12.81	5	3.32	3.32	3.61	7	3.61	3.32	12.81
Direct nonmedical costs, 2018 US $
Total direct nonmedical costs	257	3.19	1.37	7.48	96	16.37	4.97	48.83	353	4.56	1.71	13.68
Transport	244	1.96	0.95	5.29	87	5.84	2.28	14.23	331	2.55	1.09	7.29
Food, lodging, child care	122	2.28	1.37	4.74	55	27.35	13.68	41.32	176	4.56	1.66	18.23
Indirect costs—patient
Days spent seeking care	278	0.21	0.13	0.38	89	6.00	4.00	8.21	367	0.27	0.13	3.08
Days unable to work	48	14.00	7.50	22.50	9	20.00	14.00	24.00	57	14.00	8.00	24.00
Days of sick leave	34	7.00	5.00	13.00	4	15.50	6.10	22.00	38	7.00	5.00	13.00
School days lost	113	14.00	7.00	21.00	59	16.00	12.00	31.00	172	14.00	8.50	24.00
Total productivity loss, 2018 US $	74	43.01	26.33	82.75	11	71.47	46.97	156.58	85	46.97	26.33	82.75
Indirect costs—caregiver
Days spent accompanying the patient seeking care	267	0.29	0.17	1.00	88	9.06	5.61	12.13	355	0.63	0.17	5.00
Days unable to work	43	3.00	1.00	7.00	39	10.00	6.00	14.00	82	7.00	2.00	11.00
Days of sick leave	30	1.50	1.00	2.00	12	6.50	4.50	9.50	42	2.00	1.00	6.00
Total productivity loss, 2018 US $	70	7.83	3.76	18.81	48	33.85	22.57	50.78	118	15.66	7.52	37.61
Cost of illness, 2018 US $
Total cost of illness per case	286	38.06	19.88	76.22	98	188.19	144.42	309.29	384	56.35	23.80	146.48

Abbreviations: N/A, not applicable because it excludes inpatient care; 25th Pctl, 25th percentile; 75th Pctl, 75th percentile.

^aInpatient care expenses: expenses for inpatient care regardless of patient recruitment location (outpatient care, inpatient care, hospital laboratory, surgery).

^bOther services that patients did not report in the above categories (eg, medical materials or equipment for surgery).